Dr. Chang has developed and pioneered several revolutionary surgical approaches to treat complicated forms of retinal detachment, improving outcomes for patients worldwide. He was the first to use perfluoropropane gas in the management of retinal detachments caused by scar tissue proliferation (PVR) on the retina. This gas is the most frequently used gas in vitreoretinal surgery. He developed perfluorocarbon liquids, a ‘heavy liquid’ used in flattening retinal detachment, and the related surgical techniques for vitreoretinal surgery. In collaboration with Avi Grinblat, he developed a panoramic viewing system and led in the worldwide adaptation by retina surgeons to this technique. He is the recipient of several honors including the Hermann Wacker Prize from the Club Jules Gonin, Helmerich Prize from the American Society of Retinal Specialists, the Senior Honor Award and the Secretariat Award from the American Academy of Ophthalmology, the Edward Jackson Lecture, the Charles Schepens Lecture and the Alcon Research Institute Award. Consistently named as one of America’s best doctors, Dr. Chang was also recognized as one of three physicians selected as National Physician of the Year by the Castle Connolly Guides (2008).